Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379795 | 0.92 | PDE4A (0.54) | KDM4EGAAMAPTTSHRMAPK1 | |
| SCHEMBL309719 | 0.90 | KDM4E (0.46) | KDM4EGAAMAPTTSHRMAPK1 | |
| SCHEMBL9117605 | 0.83 | PRKCE (0.46) | KDM4EMAPTMAPK1ALDH1A1MEN1 | |
| SCHEMBL27090 | 0.83 | CA2 (0.54) | KDM4EGAATSHRMAPK1PDE4A | |
| SCHEMBL1066757 | 0.82 | THRA (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9116570 | 0.80 | THRA (0.51) | ALDH1A1 | |
| SCHEMBL4436990 | 0.79 | ALDH1A1 (0.50) | KDM4EGAAMAPTTSHRSMN1; SMN2 | |
| SCHEMBL20985816 | 0.78 | MAOB (0.49) | KDM4EGAAMAPTTSHRPDE4B | |
| SCHEMBL16961146 | 0.78 | S1PR1 (0.39) | KDM4EGAAMAPTTSHRMAPK1 | |
| SCHEMBL3055313 | 0.78 | ALDH1A1 (0.43) | KDM4EGAAMAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234628-A | Thermosensitive recording medium | 日本制纸株式会社 | 2024-06-21 | — | — | CN | disclosed |
| US-20240190156-A1 | THERMOSENSITIVE RECORDING MEDIUM | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 2024-06-13 | — | — | US | disclosed |
| US-20240190816-A1 | N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME | SANKO CO., LTD. (JP) | 2024-06-13 | — | — | US | disclosed |
| US-20240181797-A1 | THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD | RICOH COMPANY, LTD. (JP) | 2024-06-06 | — | — | US | disclosed |
| US-11945769-B2 | N,N′-diarylurea derivative, manufacturing method thereof, and thermosensitive recording material using same | SANKO CO., LTD. (JP) | 2024-04-02 | — | — | US | disclosed |
| US-11912052-B2 | Thermosensitive recording medium | NIPPON PAPER INDUSTRIES CO., LTD. | 2024-02-27 | — | — | US | disclosed |
| EP-4316861-A1 | HEAT-SENSITIVE RECORDING MATERIAL | Nippon Paper Industries Co., Ltd. (JP) | 2024-02-07 | — | — | EP | disclosed |
| EP-4313612-A1 | THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD | Ricoh Company, Ltd. (JP) | 2024-02-07 | — | — | EP | disclosed |
| EP-4309907-A1 | HEAT-SENSITIVE RECORDING MATERIAL | Nippon Paper Industries Co., Ltd. (JP) | 2024-01-24 | — | — | EP | disclosed |
| CN-117098670-A | Thermosensitive recording medium | 日本制纸株式会社 | 2023-11-21 | — | — | CN | disclosed |
| US-5155113-A | Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
| EP-0436902-A1 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-17 | — | — | EP | disclosed |
| US-4983609-A | Anticancer agents | OTSUKA PHARMACEUTICAL (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4497815-A | 1-(N-Substituted carbamoyl)-5-fluorouracil derivatives and the carcinostatic agents containing same as active ingredients | Ozaki, Shoichiro (JP) | 1985-02-05 | — | — | US | disclosed |
| US-3936462-A | CNS DEPRESSANT, ANALGESIC | STERLING DRUG INC. (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11945769-B2 | N,N′-diarylurea derivative, manufacturing method thereof, and thermosensitive recording material using same | SCN1A, SCN1B, NAAA | KDM4E 2891/4885GAA 3045/4885MAPT 3553/4885 |
| US-20240190816-A1 | N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME | SCN1A, SCN1B, SCN2A | KDM4E 2343/4885GAA 2519/4885MAPT 3377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.