⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25508085 | 0.77 | — | — | |
| SCHEMBL19869343 | 0.72 | NLRP3 (0.32) | — | |
| SCHEMBL21646764 | 0.69 | NLRP3 (0.30) | — | |
| SCHEMBL16843009 | 0.66 | ACHE (0.30) | — | |
| SCHEMBL18007560 | 0.61 | ACHE (0.44) | — | |
| SCHEMBL19507084 | 0.61 | — | — | |
| SCHEMBL22905508 | 0.61 | — | — | |
| SCHEMBL9274345 | 0.61 | — | — | |
| SCHEMBL9465522 | 0.58 | — | — | |
| SCHEMBL18007581 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11905252-B2 | Compounds | INFLAZOME LIMITED (IE) | 2024-02-20 | — | — | US | disclosed |