Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 9/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | STK10 | O94804 | 1/20 | 0.37 |
| ▸ | YES1 | P07947 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.37 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24493457 | 0.82 | CCNT1 (0.42) | CCNT1AXLCDK9 | |
| SCHEMBL27096001 | 0.81 | CCNT1 (0.42) | CCNT1AXLNAMPTPIM1FLT3 | |
| SCHEMBL27095983 | 0.81 | CCNT1 (0.41) | CCNT1AXLCDK9CHEK1 | |
| SCHEMBL27096029 | 0.79 | CCNT1 (0.40) | CCNT1AXLPIM1FLT3KCNH2 | |
| SCHEMBL27095816 | 0.78 | HDAC6 (0.45) | CCNT1AXLPIM1FLT3KCNH2 | |
| SCHEMBL27096077 | 0.77 | CCNT1 (0.40) | CCNT1AXLPIM1FLT3KCNH2 | |
| SCHEMBL27095908 | 0.77 | UTS2R (0.44) | CCNT1CDK9CHEK1KDM4EHSD17B10 | |
| SCHEMBL24493550 | 0.76 | MRGPRX1 (0.44) | CCNT1AXLCDK9 | |
| SCHEMBL27095996 | 0.75 | HDAC6 (0.45) | CCNT1PIM1FLT3KCNH2PIM3 | |
| SCHEMBL27095922 | 0.74 | CCNT1 (0.47) | CCNT1AXLCDK9CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240059691-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2024-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059691-A1 | ENZYME INHIBITORS | SERPINB1, XDH, ACE | CCNT1 644/4885AXL 4214/4885NAMPT 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.