⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479180 | 1.00 | — | — | |
| SCHEMBL24373489 | 0.79 | MEN1 (0.32) | — | |
| SCHEMBL29479092 | 0.79 | MEN1 (0.32) | — | |
| SCHEMBL30715963 | 0.76 | WNT3A (0.32) | — | |
| SCHEMBL25296297 | 0.76 | WNT3A (0.32) | — | |
| SCHEMBL29478826 | 0.75 | — | — | |
| SCHEMBL24373461 | 0.75 | — | — | |
| SCHEMBL26116307 | 0.70 | — | — | |
| SCHEMBL26018434 | 0.67 | TNKS2 (0.38) | — | |
| SCHEMBL25302129 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240059703-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. | 2024-02-22 | — | — | US | disclosed |