Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27097443 | 1.00 | HRH3 (0.41) | HRH3DRD2CARM1PRMT6PRMT1 | |
| SCHEMBL27097567 | 1.00 | HRH3 (0.41) | HRH3DRD2CARM1PRMT6PRMT1 | |
| SCHEMBL27097566 | 0.89 | GNAO1 (0.42) | HRH3CHRM3 | |
| SCHEMBL27097459 | 0.89 | GNAO1 (0.42) | HRH3CHRM3 | |
| SCHEMBL27097603 | 0.86 | GNAO1 (0.51) | HRH3CHRM3 | |
| SCHEMBL26496701 | 0.85 | HRH3 (0.39) | HRH3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL26157129 | 0.84 | DRD2 (0.41) | HRH3DRD2PABPC1CHRM3 | |
| SCHEMBL26157286 | 0.84 | SLC18A3 (0.38) | HRH3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL26157128 | 0.84 | DRD2 (0.41) | HRH3DRD2PABPC1CHRM3 | |
| SCHEMBL23133948 | 0.82 | HRH3 (0.47) | HRH3DRD2PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912699-B2 | Tau-protein targeting compounds and associated | MAPT, VHL, CRBN | HRH3 3443/4885DRD2 4284/4885CARM1 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.