SCHEMBL2709875

SCHEMBL2709875

Fc1ccc2c(-c3cc(F)c(F)c(F)c3)c3ccccc3c(-c3ccccc3)c2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
HPGD P15428 2/20 0.43
MAP2K4 P45985 1/20 0.42
TDP1 Q9NUW8 2/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
MAOB P27338 1/20 0.40
MAP2 P11137 1/20 0.39
ACHE P22303 1/20 0.38
PTGS2 P35354 2/20 0.38
CNR1 P21554 3/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
TNKS O95271 1/20 0.36
CCNE2 O96020 1/20 0.36
CDK4 P11802 1/20 0.36
CCND1 P24385 1/20 0.36
CCNE1 P24864 1/20 0.36
CDK2 P24941 1/20 0.36
CAMK2B Q13554 1/20 0.36
CAMK2G Q13555 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2710922 0.95 LMNA (0.42) LMNAHPGDMAP2K4TDP1CTDSP1
SCHEMBL2710377 0.95 HPGD (0.39) LMNAHPGDMAP2K4TDP1CTDSP1
SCHEMBL2711234 0.89 ACHE (0.41) LMNAHPGDMAP2K4TDP1MAP2
SCHEMBL2726789 0.89 LMNA (0.40) LMNAHPGDMAP2K4TDP1CTDSP1
SCHEMBL2728156 0.89 LMNA (0.40) LMNAHPGDMAP2K4TDP1CTDSP1
SCHEMBL12086171 0.88 LMNA (0.36) LMNAHPGDMAP2K4TDP1CTDSP1
SCHEMBL12086119 0.88 HPGD (0.36) LMNAHPGDMAP2K4TDP1CTDSP1
SCHEMBL2710353 0.88 HPGD (0.36) LMNAHPGDMAP2K4TDP1CTDSP1
SCHEMBL2713008 0.88 MAOB (0.39) LMNAHPGDMAP2K4TDP1CTDSP1
SCHEMBL2710319 0.87 ACHE (0.38) LMNAHPGDMAP2K4TDP1MAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 LMNA 1569/4885HPGD 381/4885MAP2K4 604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.