⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6395555 | 0.82 | — | — | |
| SCHEMBL3167427 | 0.81 | — | — | |
| SCHEMBL28991073 | 0.80 | TRPV1 (0.44) | — | |
| SCHEMBL29186069 | 0.80 | LMNA (0.30) | — | |
| SCHEMBL18533728 | 0.79 | ALDH1A1 (0.39) | — | |
| SCHEMBL3160911 | 0.76 | TSHR (0.35) | — | |
| SCHEMBL7631910 | 0.75 | — | — | |
| SCHEMBL3153259 | 0.75 | — | — | |
| SCHEMBL23043476 | 0.73 | — | — | |
| SCHEMBL331125 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015792-A1 | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | MSD K.K. (JP) | 2007-01-18 | — | — | US | claimed |
| US-5082845-A | Gastrointestinal | HOECHST JAPAN LIMITED (JP) | 1992-01-21 | — | — | US | claimed |
| EP-0330031-B1 | THERAPEUTIC AGENTS FOR THE TREATMENT OF PEPTIC ULCER DISEASE | HOECHST JAPAN LIMITED (JP) | 1991-12-11 | — | — | EP | claimed |
| EP-0330031-A1 | Therapeutic agents for the treatment of peptic ulcer disease | HOECHST JAPAN LIMITED (JP) | 1989-08-30 | — | — | EP | claimed |
| US-4616020-A | TREATING OBSTRUCTIVE RESPIRATORY DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-07 | — | — | US | claimed |
| EP-0075850-B1 | PHARMACEUTICAL PREPARATIONS CONTAINING VICINAL DIHYDROXYALKYL XANTHINES, PROCESS FOR THE PREPARATION OF THE XANTHINES AND THE APPROPRIATE INTERMEDIATES THEREFOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-18 | — | — | EP | claimed |
| US-20220390458-A1 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-12-08 | — | — | US | disclosed |
| WO-2021058490-A2 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-04-01 | — | — | WO | disclosed |
| EP-3795643-A1 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | Centre National de la Recherche Scientifique (FR) | 2021-03-24 | — | — | EP | disclosed |
| US-9803030-B2 | Modified saccharides | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2017-10-31 | — | — | US | disclosed |
| EP-2118145-B1 | MODIFIED SACCHARIDES | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2017-05-17 | — | — | EP | disclosed |
| CN-104497154-A | Preparation method of hydroxy butyl starch ether or hydroxy butyl modified starch ether | UNIV SOUTH CHINA TECH | 2015-04-08 | — | — | CN | disclosed |
| CN-101583629-B | Modified saccharides | NOVARTIS AG | 2013-08-21 | — | — | CN | disclosed |
| US-RE31512-E | SISOMICIN BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| EP-0019843-B1 | SISOMICIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
| US-4312859-A | ANTIBIOTICS, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| EP-0019843-A1 | Sisomicin derivatives, process for their preparation and their use as medicines | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |
| US-4235888-A | SISOMYCIN-TYPE ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |
| EP-0007996-A1 | 4,6-Di-0-(Aminoglycosyl)-1,3-diaminocyclitols, process for their preparation and pharmaceutical compositions containing them | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |
| US-4076632-A | PROTONATED DI-POLYETHOXY-MONOALKYL AMINE, UREA | THE PROCTER & GAMBLE COMPANY (US) | 1978-02-28 | — | — | US | disclosed |