Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 9/20 | 0.44 |
| ▸ | CDK2 | P24941 | 9/20 | 0.44 |
| ▸ | CDK4 | P11802 | 4/20 | 0.44 |
| ▸ | CDK1 | P06493 | 3/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 8/20 | 0.44 |
| ▸ | CCND1 | P24385 | 3/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.43 |
| ▸ | OGA | O60502 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100380 | 0.84 | CSNK2A2 (0.46) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL185115 | 0.79 | CA1 (0.44) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL13091410 | 0.75 | AOC3 (0.40) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL17065251 | 0.74 | ALDH1A1 (0.39) | — | |
| SCHEMBL2175131 | 0.74 | RAB9A (0.60) | CCNE1CDK2CDK4CDK1LMNA | |
| SCHEMBL5726205 | 0.74 | SMN1; SMN2 (0.45) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL5725304 | 0.74 | SMN1; SMN2 (0.45) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL5725310 | 0.74 | SMN1; SMN2 (0.45) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL23657121 | 0.73 | MAPT (0.58) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL13091419 | 0.73 | OGA (0.37) | CCNE1CDK2CDK4CDK1CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327814-A2 | MORPHOLINYL, PIPERAZINYL, OXAZEPANYL AND DIAZEPANYL O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2024-02-28 | — | — | EP | disclosed |