Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17030874 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTLMNAPRNP | |
| SCHEMBL27147161 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTLMNAPRNP | |
| SCHEMBL30922651 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTLMNAPRNP | |
| SCHEMBL38660623 | 0.75 | GPR35 (0.33) | — | |
| SCHEMBL19422066 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTKMT2A | |
| SCHEMBL25720390 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTKMT2A | |
| SCHEMBL25081570 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MAPTLMNATSHR | |
| SCHEMBL31470355 | 0.72 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1MAT2A | |
| SCHEMBL19695842 | 0.71 | HTR2C (0.40) | MAPTHTTMEN1KMT2A | |
| SCHEMBL25253238 | 0.71 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044667-A2 | SMALL MOLECULE INHIBITORS OF KRAS PROTEINS | MERCK SHARP & DOHME LLC (US) | 2024-02-29 | — | — | WO | disclosed |