Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 16/20 | 0.60 |
| ▸ | USP7 | Q93009 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27101127 | 0.89 | GAA (0.65) | RAB9AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL17270179 | 0.85 | ACKR3 (0.74) | ACKR3USP7RAB9AKDM4EALDH1A1 | |
| SCHEMBL2461162 | 0.81 | USP7 (0.62) | ACKR3USP7RAB9AKDM4EALDH1A1 | |
| SCHEMBL17270212 | 0.79 | ACKR3 (0.73) | ACKR3RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL17270139 | 0.78 | ACKR3 (0.80) | ACKR3 | |
| SCHEMBL7600247 | 0.77 | KDM4E (0.69) | ACKR3KDM4EALDH1A1MAPTGAA | |
| SCHEMBL2460203 | 0.76 | USP7 (0.57) | ACKR3USP7RAB9AKDM4EALDH1A1 | |
| SCHEMBL2989277 | 0.76 | RAB9A (0.78) | RAB9AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL10702311 | 0.76 | KDM4E (0.67) | ACKR3KDM4EALDH1A1MAPTGAA | |
| SCHEMBL24124175 | 0.76 | USP7 (0.52) | ACKR3USP7RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067600-A1 | SMALL MOLECULE INHIBITORS OF THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE (mtPTP) | UNIVERSITY OF KANSAS (US) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067600-A1 | SMALL MOLECULE INHIBITORS OF THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE (mtPTP) | MTCH2, TIMM50, TIMM10 | ACKR3 4806/4885USP7 3472/4885RAB9A 1640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.