Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Di(Hydroxyethyl)Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.33 |
| ▸ | NOS3 known ✓ | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 known ✓ | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 known ✓ | P35228 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL9325783 | 1.00 | TSHR (0.62) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL27615302 | 1.00 | TSHR (0.62) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL4528960 | 1.00 | TSHR (0.62) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL8642258 | 1.00 | TSHR (0.62) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL36022 | 1.00 | TSHR (0.62) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL28435040 | 1.00 | TSHR (0.62) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Triethylene Glycol SCHEMBL7049732 | 0.97 | MEN1 (0.65) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Pentaethylene Glycol SCHEMBL9614725 | 0.97 | MEN1 (0.65) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Triethylene Glycol SCHEMBL994880 | 0.97 | MEN1 (0.65) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Acetic Acid SCHEMBL21878891 | 0.97 | MEN1 (0.65) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139920-A | Halftone images; black and white photography | FUJI PHOTO FILM CO., LTD. (JP) | 1992-08-18 | — | — | US | claimed |
| JP-2311845-A | — | — | None | — | — | JP | disclosed |
| US-9000309-B2 | Electromagnetic shielding film | FUJIFILM CORPORATION (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20140234760-A1 | TRANSLUCENT ELECTROMAGNETIC SHIELD FILM, PRODUCING METHOD THEREFOR AND EMULSIFIER | FUJIFILM CORPORATION (JP) | 2014-08-21 | — | — | US | disclosed |
| US-8426749-B2 | Electromagnetic shielding film and optical filter | FUJIFILM CORPORATION (JP) | 2013-04-23 | — | — | US | disclosed |
| US-8268400-B2 | Method and apparatus for producing conductive material | FUJIFILM CORPORATION (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20120175164-A1 | ELECTROMAGNETIC SHIELDING FILM | FUJIFILM CORPORATION (JP) | 2012-07-12 | — | — | US | disclosed |
| US-8133377-B2 | Multilayer photosensitive film on transparent support; silver salt emulsion layer; exposure and devlopment; electrodeposition of silver and electroless plating | FUJIFILM CORPORATION (JP) | 2012-03-13 | — | — | US | disclosed |
| US-7796327-B2 | Light transmitting electromagnetic wave shielding film, optical filter and plasma display panel | FUJIFILM CORPORATION (JP) | 2010-09-14 | — | — | US | disclosed |
| EP-1975698-B1 | Method and apparatus for producing conductive material | FUJIFILM CORP (JP) | 2009-12-16 | — | — | EP | disclosed |
| EP-0789272-A1 | Developer for silver halide photographic photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5578414-A | CYANINE DYE, ONIUM SALT, AND HYDRAZINE COMPOUND; HIGH CONTRAST | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0736798-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |
| EP-0726489-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0716338-A2 | Fine polymer particles having heterogeneous phase structure, silver halide photographic light- sensitive material containing the fine polymer particles and image-forming method | FUJI PHOTO FILM CO., LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |
| EP-0713131-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |
| US-5139920-A | Halftone images; black and white photography | FUJI PHOTO FILM CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| JP-H02311845-A | METHOD FOR CLEANING PHOTOGRAPHIC PROCESSING DEVICE | FUJI PHOTO FILM CO LTD | 1990-12-27 | — | — | JP | disclosed |
| US-4626373-A | STORAGE STABLE BLEACH CATALYST | LEVER BROTHERS COMPANY (US) | 1986-12-02 | — | — | US | disclosed |
| EP-0141470-A2 | Manganese adjuncts, their preparation and use | UNILEVER N.V. (NL) | 1985-05-15 | — | — | EP | disclosed |