Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Triethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 6/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL21878891 | 1.00 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL5632111 | 1.00 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Acetic Acid SCHEMBL28250665 | 1.00 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL27352527 | 1.00 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL7049732 | 1.00 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL28411928 | 1.00 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Pentaethylene Glycol SCHEMBL9614725 | 1.00 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Acetic Acid SCHEMBL21878939 | 1.00 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL22689479 | 0.97 | MEN1 (0.61) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL4888771 | 0.97 | MEN1 (0.61) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080897-A | Blocking remover, and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-119841661-A | Ceramic slurry, porous ceramic, and preparation method and application thereof | 湖北芯陶科技有限公司 | 2025-04-18 | — | — | CN | claimed |
| US-12240961-B2 | Cellulose acetate resin composition | DAICEL CORPORATION (JP) | 2025-03-04 | — | — | US | claimed |
| CN-114784272-B | Environment-friendly lithium iron phosphate battery and preparation method thereof | 江西安驰新能源科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| US-20230192993-A1 | CELLULOSE ACETATE RESIN COMPOSITION | DAICEL CORPORATION (JP) | 2023-06-22 | — | — | US | claimed |
| CN-114933467-A | Ceramic prepared by using machine-made sand sludge as raw material and manufacturing method thereof | 丽水学院 | 2022-08-23 | — | — | CN | claimed |
| CN-114784272-A | Environment-friendly lithium iron phosphate battery and preparation method thereof | 江西安驰新能源科技有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-107759230-B | Toughened ceramic gel injection molding method | 无锡特科精细陶瓷有限公司 | 2020-09-01 | — | — | CN | claimed |
| CN-107056297-A | Re:Lu2O3Crystalline ceramics and its gel injection moulding preparation | 中国科学院长春光学精密机械与物理研究所 | 2017-08-18 | — | — | CN | claimed |
| CN-105777066-A | Longquan celadon made from rare earth tailings and manufacture method thereof | 丽水学院 | 2016-07-20 | — | — | CN | claimed |
| EP-1852415-A1 | Process for the preparation of N-monosubstituted beta-amino alcohols | LONZA AG (CH) | 2007-11-07 | — | — | EP | claimed |
| EP-1539673-B1 | PROCESS FOR THE PREPARATION OF N -MONOSUBSTITUTED BETA-AMINO ALCOHOLS | LONZA AG (CH) | 2007-10-03 | — | — | EP | claimed |
| US-20050256318-A1 | Process for the preparation of n-monosubstituted beta-amino alcohols | LONZA AG (CH) | 2005-11-17 | — | — | US | claimed |
| JP-2005532383-A | — | — | 2005-10-27 | — | — | JP | claimed |
| EP-1539673-A1 | PROCESS FOR THE PREPARATION OF i N /i -MONOSUBSTITUTED &bgr;-AMINO ALCOHOLS | LONZA AG (CH) | 2005-06-15 | — | — | EP | claimed |
| WO-2004005239-A1 | PROCESS FOR THE PREPARATION OF N-MONOSUBSTITUTED β-AMINO ALCOHOLS | LONZA AG (CH) | 2004-01-15 | — | — | WO | claimed |
| EP-1044259-A1 | MICROEMULSION CLEANING COMPOSITIONS | Colgate-Palmolive Company (US) | 2000-10-18 | — | — | EP | claimed |
| WO-1999035237-A1 | MICROEMULSION CLEANING COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 1999-07-15 | — | — | WO | claimed |
| US-5905064-A | MIXTURE OF SULFONATE SURFACTANT WITH ETHOXYALKYL ETHER SULFATE, A SOLUBILIZER WITH ORGANIC COMPOUNDS WATER INSOLUBLE HYDROCARBON AND WATER. | COLGATE-PALMOLIVE CO. (US) | 1999-05-18 | — | — | US | claimed |
| US-4168984-A | ADDING A GLYCOL ACETATE | MARTIN MARIETTA CORPORATION (US) | 1979-09-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256318-A1 | Process for the preparation of n-monosubstituted beta-amino alcohols | ADH1C, ADH1A, HRH2 | ADRB2 30/4885MEN1 2813/4885KMT2A 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.