Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.56 |
| ▸ | CDC25A | P30304 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27106960 | 1.00 | TLR7 (0.56) | TLR7CDC25ACDC25BIRAK4ALDH1A1 | |
| SCHEMBL27141573 | 0.91 | TLR7 (0.56) | TLR7CDC25ACDC25BIRAK4ALDH1A1 | |
| SCHEMBL27141574 | 0.91 | TLR7 (0.56) | TLR7CDC25ACDC25BIRAK4ALDH1A1 | |
| SCHEMBL27106466 | 0.89 | TLR7 (0.55) | TLR7HPGDSHPGDRAB9ANPC1 | |
| SCHEMBL27153238 | 0.86 | TLR7 (0.44) | TLR7CDC25ACDC25BIRAK4ALDH1A1 | |
| SCHEMBL27153239 | 0.86 | TLR7 (0.44) | TLR7CDC25ACDC25BIRAK4ALDH1A1 | |
| SCHEMBL27106972 | 0.84 | TLR7 (0.56) | TLR7CDC25ACDC25BIRAK4ALDH1A1 | |
| SCHEMBL26012509 | 0.81 | SREBF2 (0.47) | IRAK4HPGDSRAB9ANPC1POLB | |
| SCHEMBL30807227 | 0.81 | HDAC1 (0.42) | KDM4EHPGDSPOLBHDAC1HDAC6 | |
| SCHEMBL30807254 | 0.81 | PIN1 (0.48) | TLR7CDC25ACDC25BHPGDSRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044744-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2024-02-29 | — | — | WO | disclosed |