Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 5/20 | 0.52 |
| ▸ | CDC25A | P30304 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27141574 | 0.91 | TLR7 (0.56) | TLR7ALDH1A1KDM4EHPGDHPGDS | |
| SCHEMBL27141573 | 0.91 | TLR7 (0.56) | TLR7ALDH1A1KDM4EHPGDHPGDS | |
| SCHEMBL27107002 | 0.87 | TLR7 (0.50) | TLR7ALDH1A1KDM4EHPGDHPGDS | |
| SCHEMBL27106519 | 0.86 | TLR7 (0.57) | TLR7ALDH1A1HPGDHPGDSPIN1 | |
| SCHEMBL27106960 | 0.84 | TLR7 (0.56) | TLR7ALDH1A1KDM4EHPGDHPGDS | |
| SCHEMBL27106959 | 0.84 | TLR7 (0.56) | TLR7ALDH1A1KDM4EHPGDHPGDS | |
| SCHEMBL31364471 | 0.84 | TLR7 (0.49) | TLR7ALDH1A1KDM4EHPGDHPGDS | |
| SCHEMBL27107383 | 0.83 | HPGDS (0.53) | TLR7HPGDHPGDSPIN1NPC1 | |
| SCHEMBL27108674 | 0.82 | TLR7 (0.47) | TLR7HPGDHPGDSPIN1CDC25A | |
| SCHEMBL27106202 | 0.81 | TLR7 (0.54) | TLR7HPGDHPGDSPIN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044744-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2024-02-29 | — | — | WO | disclosed |