SCHEMBL2710697

SCHEMBL2710697

COc1cc(F)c(-c2c3ccc(F)cc3c(-c3c(F)c(F)c(OC)c(F)c3F)c3c(F)c(F)c(F)c(F)c23)c(F)c1

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.31
MAPK14 Q16539 1/20 0.31
TRPA1 O75762 2/20 0.31
NFE2L2 Q16236 1/20 0.31
MAP2K4 P45985 1/20 0.30
PMM2 O15305 2/20 0.30
MIF P14174 2/20 0.30
MPI P34949 2/20 0.30
PHOSPHO1 Q8TCT1 2/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2942680 0.95 NQO2 (0.34) NQO2MAPK14TRPA1NFE2L2MAP2K4
SCHEMBL2725527 0.92 NFE2L2 (0.33) NQO2MAPK14TRPA1NFE2L2MAP2K4
SCHEMBL2936476 0.92 NQO2 (0.36) NQO2MAPK14TRPA1NFE2L2MAP2K4
SCHEMBL2725666 0.90 HSD17B10 (0.33) NFE2L2
SCHEMBL12086086 0.90 HSD17B10 (0.33) NFE2L2
SCHEMBL2712513 0.90 HSD17B10 (0.33) NFE2L2
SCHEMBL2711035 0.89 NQO2 (0.33) NQO2MAPK14TRPA1NFE2L2MAP2K4
SCHEMBL2942794 0.89 MAOB (0.33) NQO2MAPK14TRPA1NFE2L2MAP2K4
SCHEMBL2943946 0.88 TUBB4A (0.33) NQO2MAPK14TRPA1NFE2L2MIF
SCHEMBL2725964 0.88 HSD17B10 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 NQO2 283/4885MAPK14 3742/4885TRPA1 2295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.