⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2112419 | 0.93 | LMNA (0.40) | — | |
| SCHEMBL2109550 | 0.91 | LMNA (0.39) | — | |
| SCHEMBL2110908 | 0.91 | LMNA (0.39) | — | |
| SCHEMBL2110576 | 0.91 | LMNA (0.39) | — | |
| SCHEMBL269240 | 0.84 | — | — | |
| SCHEMBL3781240 | 0.82 | LMNA (0.52) | — | |
| SCHEMBL269245 | 0.79 | — | — | |
| SCHEMBL270334 | 0.75 | — | — | |
| SCHEMBL3946926 | 0.75 | — | — | |
| SCHEMBL1962475 | 0.75 | ADH1B (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 704 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954532-A | Anti-tumor multi-drug resistance of heteroaryl amide compounds, application of heteroaryl amide compounds in treating cancer and protein-drug molecular compound | 上海交通大学医学院附属瑞金医院 | 2020-11-17 | — | — | CN | claimed |
| US-20200325156-A1 | HETEROARYL AMIDE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS THEREOF, AND APPLICATIONS THEREOF | RUI JIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE (CN) | 2020-10-15 | — | — | US | claimed |
| EP-3705481-A1 | HETEROARYL AMIDE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS THEREOF, AND APPLICATIONS THEREOF | Rui Jin Hospital Affiliated To Shanghai Jiao Tong University School of Medicine (CN) | 2020-09-09 | — | — | EP | claimed |
| CN-111295387-A | Heteroaryl amide compound, preparation method thereof, medicinal composition and application thereof | 上海交通大学医学院附属瑞金医院 | 2020-06-16 | — | — | CN | claimed |
| CN-111170988-A | Pyrazole formamide derivative containing substituted sulfimide acyl aryl, and preparation method and application thereof | 南开大学 | 2020-05-19 | — | — | CN | claimed |
| WO-2019196111-A1 | ANTI-TUMOR MULTIDRUG RESISTANCE OF HETEROARYL AMIDE COMPOUND, USE IN TREATMENT OF CANCERS AND PROTEIN-DRUG MOLECULAR COMPLEX | 上海交通大学医学院附属瑞金医院 | 2019-10-17 | — | — | WO | claimed |
| WO-2024106438-A1 | AMIDE COMPOUNDS OR SALTS THEREOF, BACTERICIDAL AGENTS FOR AGRICULTURE AND HORTICULTURE CONTAINING SAID COMPOUNDS, AND METHOD OF USING SAME | 日本農薬株式会社 | 2024-05-23 | — | — | WO | disclosed |
| CN-113226310-B | 15-PGDH inhibitors | 杏林制药株式会社 | 2024-03-19 | — | — | CN | disclosed |
| WO-2024043261-A1 | AZO COMPOUND OR SALT THEREOF, AND POLARIZING FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME | 日本化薬株式会社 | 2024-02-29 | — | — | WO | disclosed |
| WO-2024005032-A1 | AZEPANDIONE DERIVATIVE OR SALT THEREOF, HARMFUL ORGANISM CONTROL AGENT CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | 株式会社ADEKA | 2024-01-04 | — | — | WO | disclosed |
| CN-114026199-B | Polarized light emitting film, polarized light emitting panel and display device containing water-soluble coumarin compound or salt thereof | 日本化药株式会社 | 2023-12-26 | — | — | CN | disclosed |
| WO-2023210792-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE OF BOTH OF FOREGOING | 日本農薬株式会社 | 2023-11-02 | — | — | WO | disclosed |
| US-11802208-B2 | Stilbene-based compound or salt thereof, and polarizing film, polarizing plate, and display device | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2023-10-31 | — | — | US | disclosed |
| EP-0432893-A2 | Benzoxazine derivatives, their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4729992-A | Cephalosporin esters, their production and use | TATSUO CHEMICAL IND., LTD. (JP) | 1988-03-08 | — | — | US | disclosed |
| US-4698339-A | BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0159899-A2 | Cephalosporin esters, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-10-30 | — | — | EP | disclosed |
| EP-0137403-A2 | Carbapenems, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-17 | — | — | EP | disclosed |