SCHEMBL27110010

SCHEMBL27110010

Ic1cc2ccnnc2cc1I

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
GLA P06280 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19001489 0.76 NOS1 (0.35) ALDH1A1GLAMAPTHPGDACHE
SCHEMBL19001488 0.76 NOS1 (0.31) MAPT
SCHEMBL29994991 0.74 ALDH1A1 (0.50) ALDH1A1GLAMAPTHPGDACHE
SCHEMBL22045620 0.74 CSNK1D (0.36) ALDH1A1GLAMAPTHPGDACHE
SCHEMBL1094981 0.74 ALDH1A1 (0.50) ALDH1A1GLAMAPTHPGDACHE
SCHEMBL27110049 0.74
SCHEMBL7784287 0.73 NPC1 (0.34) ALDH1A1GLAMAPTHPGDACHE
SCHEMBL15124134 0.73 ALDH1A1 (0.48) ALDH1A1GLAMAPTHPGDACHE
SCHEMBL15124859 0.73 ALDH1A1 (0.48) ALDH1A1GLAMAPTHPGDACHE
SCHEMBL8404464 0.73 NQO2 (0.43) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-02-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067664-A1 Organic Compound, Light-Emitting Device, Display Device, Electronic Device, Light-Emitting Apparatus, and Lighting Device CCND1, CCND2, DRD1 ALDH1A1 180/4885GLA 1876/4885MAPT 3321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.