SCHEMBL27112906

SCHEMBL27112906

CC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.44
▸ NPY1R P25929 9/20 0.44
▸ NPY5R Q15761 8/20 0.44
▸ NPY2R P49146 5/20 0.44
▸ SIRT5 Q9NXA8 2/20 0.40
▸ SIRT6 Q8N6T7 1/20 0.36
▸ SIRT1 Q96EB6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27113592 0.93 NPY4R (0.47) NPY4RNPY1RNPY5RNPY2RSIRT5
SCHEMBL14012343 0.92 NPY4R (0.41) NPY4RNPY1RNPY5RNPY2RSIRT5
SCHEMBL14845337 0.90 NPY4R (0.38) NPY4RNPY1RNPY5RNPY2RSIRT5
SCHEMBL24765373 0.89 NPY4R (0.42) NPY4RNPY1RNPY5RNPY2RSIRT5
SCHEMBL27113590 0.86 NPY4R (0.41) NPY4RNPY1RNPY5RNPY2RSIRT5
SCHEMBL19069865 0.83 NPY4R (0.47) NPY4RNPY1RNPY5RNPY2RSIRT5
SCHEMBL27113031 0.83 ENPEP (0.41) NPY4RNPY1RNPY5RNPY2R
SCHEMBL24157931 0.82 NPY4R (0.40) NPY4RNPY1RNPY5RNPY2RSIRT5
SCHEMBL16439029 0.82 NPY4R (0.47) NPY4RNPY1RNPY5RNPY2RSIRT5
SCHEMBL18264748 0.82 NPY4R (0.47) NPY4RNPY1RNPY5RNPY2RSIRT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SUPERTRANS MEDICAL LTD (IL) 2024-02-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SLC7A1, ABCB11, SLC1A5 NPY4R 3178/4885NPY1R 3757/4885NPY5R 2907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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