Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 4/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 3/20 | 0.52 |
| ▸ | BCR | P11274 | 3/20 | 0.52 |
| ▸ | SRC | P12931 | 2/20 | 0.52 |
| ▸ | PRKCA | P17252 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.52 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.51 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27115033 | 0.91 | PIK3CG (0.56) | PIK3CGPIK3CAPIK3CBPRKCDABL1 | |
| SCHEMBL27114961 | 0.86 | PIK3CG (0.59) | PIK3CGPIK3CAPIK3CBPRKCDROCK2 | |
| SCHEMBL8489648 | 0.84 | PIK3CG (0.76) | PIK3CGPIK3CAPIK3CBROCK2ROCK1 | |
| SCHEMBL27115034 | 0.78 | PIK3CG (0.60) | PIK3CGPIK3CAPIK3CBPRKCDABL1 | |
| SCHEMBL8837795 | 0.78 | ABL1 (0.80) | PIK3CGPIK3CAPIK3CBPRKCDPRKACA | |
| SCHEMBL27116599 | 0.78 | ABL1 (0.62) | PIK3CGPIK3CAPRKCDABL1BCR | |
| SCHEMBL27116472 | 0.77 | CDK2 (0.57) | PIK3CGPIK3CAPIK3CBPRKACADYRK1A | |
| SCHEMBL27115444 | 0.77 | PIK3CA (0.69) | PIK3CGPIK3CAPIK3CBDYRK1AABL1 | |
| SCHEMBL5733933 | 0.77 | CAMK2D (0.71) | PIK3CGPIK3CAPIK3CBPRKCDABL1 | |
| SCHEMBL13924595 | 0.75 | SYK (0.72) | PIK3CGPIK3CAPIK3CBSRCSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | claimed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |