Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.59 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27115034 | 0.91 | PIK3CG (0.60) | PIK3CGPIK3CAPIK3CBCDK5MTOR | |
| SCHEMBL27115896 | 0.88 | PIK3CG (0.76) | PIK3CGPIK3CAPIK3CBCDK5MTOR | |
| SCHEMBL27114882 | 0.86 | PIK3CG (0.54) | PIK3CGPIK3CAPIK3CBCDK5PRKCD | |
| SCHEMBL27115445 | 0.82 | PIK3CG (0.66) | PIK3CGPIK3CAPIK3CBCDK5MTOR | |
| SCHEMBL27116600 | 0.81 | ABL1 (0.57) | PIK3CGPIK3CAPIK3CBCDK5SMG1 | |
| SCHEMBL27116528 | 0.80 | PIK3CG (0.64) | PIK3CGPIK3CAPIK3CBCDK5MTOR | |
| SCHEMBL5733563 | 0.80 | MAPT (0.72) | PIK3CGPIK3CAPIK3CBCDK5MTOR | |
| SCHEMBL8837800 | 0.80 | ABL1 (0.76) | PIK3CGPIK3CAPIK3CBCDK5MTOR | |
| SCHEMBL27115339 | 0.78 | PIK3CG (0.55) | PIK3CGPIK3CAPIK3CBCDK5MTOR | |
| SCHEMBL27116598 | 0.78 | PIK3CG (0.83) | PIK3CGPIK3CAPIK3CBCDK5MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | claimed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |