⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27122864 | 0.85 | SIGMAR1 (0.32) | — | |
| SCHEMBL27117909 | 0.80 | SIGMAR1 (0.32) | — | |
| SCHEMBL27122537 | 0.79 | SIGMAR1 (0.32) | — | |
| SCHEMBL27115911 | 0.75 | — | — | |
| SCHEMBL19116890 | 0.75 | HDAC8 (0.30) | — | |
| SCHEMBL27115895 | 0.75 | — | — | |
| SCHEMBL27120133 | 0.73 | SIGMAR1 (0.32) | — | |
| SCHEMBL27122611 | 0.73 | HRH3 (0.31) | — | |
| SCHEMBL25993687 | 0.72 | PRMT5 (0.32) | — | |
| SCHEMBL27118055 | 0.71 | METAP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076650-B1 | 3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2024-02-28 | — | — | EP | disclosed |