Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930925 | 0.89 | HSP90AA1 (0.37) | RORCCFTRMARK4ALDH1A1MAPK1 | |
| SCHEMBL1930756 | 0.83 | RORC (0.45) | RORCMARK4ALDH1A1MAPK1LMNA | |
| SCHEMBL1932041 | 0.81 | RORC (0.41) | RORCALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1931663 | 0.81 | MAPK1 (0.43) | ALDH1A1MAPK1LMNAKMT2ACYP3A4 | |
| SCHEMBL1931559 | 0.81 | ALDH1A1 (0.40) | CFTRALDH1A1MAPK1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL1931669 | 0.81 | MAPK1 (0.42) | ALDH1A1MAPK1LMNAKMT2ACYP3A4 | |
| SCHEMBL1931390 | 0.80 | ALDH1A1 (0.40) | CFTRALDH1A1MAPK1LMNAKMT2A | |
| SCHEMBL1930915 | 0.79 | ALDH1A1 (0.41) | CFTRALDH1A1MAPK1LMNAKMT2A | |
| SCHEMBL1930678 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPK1LMNAKMT2ACYP3A4 | |
| SCHEMBL1931173 | 0.77 | ALDH1A1 (0.39) | CFTRALDH1A1MAPK1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861403-B1 | NOVEL IMIDAZO[1,5-A]PYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SA (FR) | 2012-05-02 | — | — | EP | disclosed |
| EP-1861403-A1 | NOVEL IMIDAZO[1,5-A]PYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006097625-A1 | NOVEL IMIDAZO[1,5-A]PYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-AVENTIS (FR) | 2006-09-21 | — | — | WO | disclosed |