Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23192496 | 0.86 | FTO (0.62) | GSTP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13663813 | 0.83 | MAPT (0.49) | GSTP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19372812 | 0.81 | GSTP1 (0.39) | GSTP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16745253 | 0.81 | HPGD (0.48) | GSTP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31580086 | 0.81 | HPGD (0.48) | GSTP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20353110 | 0.80 | ALDH1A1 (0.52) | GSTP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13662232 | 0.79 | MAPT (0.47) | GSTP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL18874719 | 0.79 | FTO (0.52) | GSTP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31580046 | 0.78 | FTO (0.66) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL9610878 | 0.78 | FTO (0.66) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024042146-A2 | COVALENT FLUORESCENT PROBES FOR CANNABINOID RECEPTOR 2 | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-29 | — | — | WO | disclosed |