Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26907427 | 1.00 | PIK3CD (0.53) | PIK3CDUSP30GPR119 | |
| SCHEMBL30722716 | 1.00 | PIK3CD (0.53) | PIK3CDUSP30GPR119 | |
| SCHEMBL26668703 | 0.93 | CHEK2 (0.49) | PIK3CDUSP30GPR119 | |
| SCHEMBL26668718 | 0.93 | CHEK2 (0.49) | PIK3CDUSP30GPR119 | |
| SCHEMBL26668657 | 0.93 | GPR119 (0.54) | PIK3CDGPR119 | |
| SCHEMBL26125483 | 0.90 | USP30 (0.45) | PIK3CDUSP30GPR119 | |
| SCHEMBL19023406 | 0.85 | USP30 (0.46) | PIK3CDUSP30GPR119 | |
| SCHEMBL27115842 | 0.83 | BTK (0.42) | PIK3CD | |
| SCHEMBL26988825 | 0.83 | BTK (0.42) | PIK3CD | |
| SCHEMBL26907230 | 0.83 | BTK (0.42) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174662-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | CILAG AG (CH) | 2024-05-30 | — | — | US | disclosed |
| EP-4284802-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | Janssen Biotech, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| WO-2022165530-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | JANSSEN BIOTECH, INC. (US) | 2022-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174662-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | SIK2, SIK1, SGK2 | PIK3CD 389/4885USP30 3165/4885GPR119 2129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.