SCHEMBL30722716

SCHEMBL30722716

Cn1cc(O[C@@H]2CCN(C(=O)OC(C)(C)C)C2)cn1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 14/20 0.53
▸ USP30 Q70CQ3 2/20 0.49
▸ GPR119 Q8TDV5 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26907427 1.00 PIK3CD (0.53) PIK3CDUSP30GPR119
SCHEMBL27117708 1.00 PIK3CD (0.53) PIK3CDUSP30GPR119
SCHEMBL26668703 0.93 CHEK2 (0.49) PIK3CDUSP30GPR119
SCHEMBL26668718 0.93 CHEK2 (0.49) PIK3CDUSP30GPR119
SCHEMBL26668657 0.93 GPR119 (0.54) PIK3CDGPR119
SCHEMBL26125483 0.90 USP30 (0.45) PIK3CDUSP30GPR119
SCHEMBL19023406 0.85 USP30 (0.46) PIK3CDUSP30GPR119
SCHEMBL27115842 0.83 BTK (0.42) PIK3CD
SCHEMBL26988825 0.83 BTK (0.42) PIK3CD
SCHEMBL26907230 0.83 BTK (0.42) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4551575-A2 TREM2 MODULATORS Muna Therapeutics ApS (DK) 2025-05-14 — — EP disclosed
CN-119403806-A TREM2 modulators 穆纳治疗有限公司 2025-02-07 — — CN disclosed
WO-2024008722-A2 TREM2 MODULATORS MUNA THERAPEUTICS APS (DK) 2024-01-11 — — WO disclosed
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