SCHEMBL2711997

SCHEMBL2711997

N#CCCCSCOCSCCCC#N

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7835392 0.83 TSHR (0.45) TSHRALDH1A1TDP1
SCHEMBL19971895 0.78 ALDH1A1 (0.30) ALDH1A1TDP1
SCHEMBL1009215 0.74
SCHEMBL2711995 0.74
SCHEMBL17935751 0.74 TSHR (0.38) TSHRALDH1A1TDP1
SCHEMBL24688765 0.74
SCHEMBL28753262 0.74 ALDH1A1 (0.35) TSHRALDH1A1TDP1
SCHEMBL11870679 0.72 TSHR (0.41) TSHRALDH1A1TDP1
SCHEMBL7846196 0.72
SCHEMBL8653772 0.70 TSHR (0.46) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1795536-B1 PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA NIPPON SHINYAKU CO LTD (JP) 2012-05-02 EP disclosed
US-20070282097-A1 Phosphoramidite Compound And Method For Producing Oligo-Rna NIPPON SHINYAKU CO., LTD. (JP) 2007-12-06 US disclosed
EP-1795536-A1 PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA Nippon Shinyaku Co., Ltd. (JP) 2007-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070282097-A1 Phosphoramidite Compound And Method For Producing Oligo-Rna NSUN2, NSUN3, XRN2 TSHR 1960/4885ALDH1A1 4198/4885TDP1 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.