Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27119471 | 0.92 | SIGMAR1 (0.33) | SIGMAR1SLC6A4KCNH2 | |
| SCHEMBL25993613 | 0.82 | TLR7 (0.32) | SIGMAR1SLC6A4KCNH2 | |
| SCHEMBL27120147 | 0.79 | NPC1 (0.34) | — | |
| SCHEMBL27120437 | 0.76 | CHRM1 (0.36) | SIGMAR1SLC6A4KCNH2 | |
| SCHEMBL24692266 | 0.76 | NR1H2 (0.37) | — | |
| SCHEMBL27117909 | 0.74 | SIGMAR1 (0.32) | SIGMAR1KCNH2 | |
| SCHEMBL27122483 | 0.74 | SIGMAR1 (0.32) | SIGMAR1KCNH2 | |
| SCHEMBL27123114 | 0.71 | SIGMAR1 (0.33) | SIGMAR1KCNH2 | |
| SCHEMBL27120133 | 0.69 | SIGMAR1 (0.32) | SIGMAR1KCNH2 | |
| SCHEMBL25993189 | 0.68 | KCNH2 (0.41) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076650-B1 | 3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2024-02-28 | — | — | EP | disclosed |