Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 12/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.37 |
| ▸ | ATR | Q13535 | 12/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 10/20 | 0.36 |
| ▸ | ATM | Q13315 | 9/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 5/20 | 0.34 |
| ▸ | SERPINA2 | P20848 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541796 | 1.00 | PRKDC (0.37) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL27124103 | 0.91 | ATR (0.39) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL21541791 | 0.91 | ATR (0.39) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL21541741 | 0.89 | ATR (0.38) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL27127196 | 0.89 | ATR (0.38) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL21541859 | 0.89 | PRKDC (0.39) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL21541730 | 0.88 | PRKDC (0.40) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL27132009 | 0.88 | EML4 (0.34) | MELKMTORHSD11B1EML4ALK | |
| SCHEMBL21541766 | 0.88 | EML4 (0.34) | MELKMTORHSD11B1EML4ALK | |
| SCHEMBL21541732 | 0.87 | PRKDC (0.40) | PRKDCPIK3CBATRATRIPATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | disclosed |