Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EML4 | Q9HC35 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 3/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | MELK | Q14680 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541766 | 1.00 | EML4 (0.34) | EML4ALKCSF1RCDK4CDK6 | |
| SCHEMBL21541779 | 0.92 | CDK4 (0.35) | CSF1RCDK4CDK6MTORHSD11B1 | |
| SCHEMBL29558902 | 0.92 | CDK4 (0.35) | CSF1RCDK4CDK6MTORHSD11B1 | |
| SCHEMBL21541733 | 0.91 | CDK4 (0.37) | CSF1RCDK4CDK6MTORS1PR1 | |
| SCHEMBL21541746 | 0.90 | CDK4 (0.37) | CSF1RCDK4CDK6MTORHSD11B1 | |
| SCHEMBL21541716 | 0.89 | CDK4 (0.34) | CSF1RCDK4CDK6MTORHSD11B1 | |
| SCHEMBL21541857 | 0.89 | CDK4 (0.35) | CSF1RCDK4CDK6S1PR1FGFR3 | |
| SCHEMBL21541796 | 0.88 | PRKDC (0.37) | EML4ALKCSF1RCDK4CDK6 | |
| SCHEMBL27123583 | 0.88 | PRKDC (0.37) | EML4ALKCSF1RCDK4CDK6 | |
| SCHEMBL21541808 | 0.88 | S1PR1 (0.37) | CSF1RCDK4CDK6MTORS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | disclosed |