Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955041 | 0.76 | CHUK (0.44) | ADORA3L3MBTL1CHUKKDM4EGABRP | |
| SCHEMBL6388405 | 0.76 | AHR (0.52) | ADORA3L3MBTL1CHUKKDM4EGABRP | |
| SCHEMBL16294882 | 0.74 | MAP2 (0.58) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL1254486 | 0.74 | AHR (0.55) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3842654 | 0.74 | CHUK (0.50) | ADORA3L3MBTL1CHUKKDM4EGABRP | |
| SCHEMBL29956558 | 0.74 | AHR (0.55) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13242405 | 0.73 | L3MBTL1 (0.49) | ADORA3L3MBTL1CHUKKDM4EGABRP | |
| SCHEMBL1569016 | 0.72 | MAP2 (0.52) | ADORA3L3MBTL1CHUKKDM4EGABRP | |
| SCHEMBL16295995 | 0.72 | CHUK (0.50) | CHUKKDM4EALDH1A1HPGD | |
| SCHEMBL16294622 | 0.72 | MAP2 (0.46) | CHUKKDM4EGABRPGABRDIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801499-B1 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS INC (US) | 2024-02-28 | — | — | EP | disclosed |