Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952910 | 0.86 | ACHE (0.47) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL2347419 | 0.79 | CHUK (0.47) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL29956795 | 0.79 | CHUK (0.47) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL29856788 | 0.79 | KDM5A (0.48) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL27125285 | 0.76 | ADORA3 (0.48) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL6388405 | 0.76 | AHR (0.52) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL6488869 | 0.74 | SMN1; SMN2 (0.51) | CHUKKDM4EGABRPGABRDIKBKB | |
| Hydrochloric Acid SCHEMBL3842654 | 0.74 | CHUK (0.50) | CHUKKDM4EGABRPGABRDIKBKB | |
| SCHEMBL248974 | 0.74 | HPGD (0.61) | ALDH1A1HPGDSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL29378092 | 0.74 | HPGD (0.61) | ALDH1A1HPGDSMN1; SMN2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |