SCHEMBL2712581

SCHEMBL2712581

Fc1c(F)c(C(F)(F)F)c(F)c(F)c1-c1c2ccccc2cc2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALOX5 P09917 1/20 0.37
NISCH Q9Y2I1 1/20 0.35
CES1 P23141 1/20 0.35
PDPK1 O15530 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 2/20 0.34
HIF1A Q16665 1/20 0.34
CYP1B1 Q16678 1/20 0.34
HTR2A P28223 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
CYP1A2 P05177 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2710306 0.86 MEN1 (0.42) MEN1KMT2AALDH1A1GAAKDM4E
SCHEMBL2712156 0.84 MEN1 (0.41) MEN1KMT2AALDH1A1GAAKDM4E
SCHEMBL1658080 0.84 ALOX5 (0.44) MEN1KMT2AALOX5NISCHCES1
SCHEMBL2712747 0.81 MEN1 (0.38) MEN1KMT2AALDH1A1HPRT1
SCHEMBL2943549 0.81 MEN1 (0.38) MEN1KMT2AALDH1A1GAAKDM4E
SCHEMBL18912085 0.80 NQO1 (0.42) MEN1KMT2AALOX5ALDH1A1KDM4E
SCHEMBL2712696 0.80 MEN1 (0.37) MEN1KMT2AALDH1A1HPRT1
SCHEMBL27875507 0.80 CES1 (0.35) MEN1KMT2ACES1ALDH1A1HSD17B10
SCHEMBL2709970 0.79 MEN1 (0.36) MEN1KMT2AALDH1A1GAACYP1A2
SCHEMBL2712748 0.78 MEN1 (0.38) MEN1KMT2AALDH1A1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220145172-A1 POLYMERIC ORGANIC NANOPARTICLES WITH ENHANCED EMISSION Sony Group Corporation (JP) 2022-05-12 US disclosed
US-11230663-B2 Polymeric organic nanoparticles with enhanced emission SONY CORPORATION (JP) 2022-01-25 US disclosed
US-20200166502-A1 SENSOR FOR THE DETECTION OF BIOMOLECULES SONY CORPORATION (JP) 2020-05-28 US disclosed
US-20190085237-A1 POLYMERIC ORGANIC NANOPARTICLES WITH ENHANCED EMISSION SONY CORPORATION (JP) 2019-03-21 US disclosed
WO-2017167631-A1 POLYMERIC ORGANIC NANOPARTICLES WITH ENHANCED EMISSION SONY CORPORATION (JP) 2017-10-05 WO disclosed
WO-2017167633-A1 SENSOR FOR THE DETECTION OF BIOMOLECULES SONY CORPORATION (JP) 2017-10-05 WO disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed