Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 3/20 | 0.32 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 2/20 | 0.31 |
| ▸ | USP7 | Q93009 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 4/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30781259 | 0.86 | TBK1 (0.32) | KITUSP7KCNH2RET | |
| SCHEMBL30781441 | 0.86 | USP7 (0.34) | KITUSP7KCNH2 | |
| SCHEMBL27127505 | 0.85 | USP7 (0.37) | USP7KCNH2 | |
| SCHEMBL30781345 | 0.85 | USP7 (0.37) | USP7KCNH2 | |
| SCHEMBL27120927 | 0.84 | USP7 (0.40) | KITUSP7KCNH2RET | |
| Hydrochloric Acid SCHEMBL27141994 | 0.84 | USP7 (0.36) | USP7KCNH2 | |
| Hydrochloric Acid SCHEMBL30781433 | 0.84 | USP7 (0.36) | USP7KCNH2 | |
| SCHEMBL27123023 | 0.83 | USP7 (0.36) | KITUSP7KCNH2 | |
| SCHEMBL27124040 | 0.83 | USP7 (0.35) | USP7KCNH2 | |
| SCHEMBL27125864 | 0.82 | KIT (0.42) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150362-A1 | Substituted Pyrrolotriazines | MOLECURE S.A. (PL) | 2024-05-09 | — | — | US | disclosed |
| WO-2024042494-A1 | SUBSTITUTED PYRROLOTRIAZINES | MOLECURE SA (PL) | 2024-02-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150362-A1 | Substituted Pyrrolotriazines | USP7, UBA7, USP5 | RORC 865/4885KIT 3180/4885ACACB 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.