Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 4/20 | 0.53 |
| ▸ | ARG2 | P78540 | 3/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28334310 | 1.00 | ARG1 (0.53) | ARG1ARG2GGT1KDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL2713261 | 0.98 | ARG1 (0.51) | ARG1ARG2GGT1KDM4EMAPK1 | |
| SCHEMBL2757819 | 0.98 | ARG1 (0.54) | ARG1ARG2GGT1KDM4EMAPK1 | |
| SCHEMBL29378890 | 0.84 | KDM4E (0.54) | ARG1ARG2GGT1KDM4EMAPK1 | |
| SCHEMBL28429572 | 0.81 | ARG1 (0.53) | ARG1ARG2GGT1KDM4EMAPK1 | |
| SCHEMBL31370370 | 0.81 | ARG1 (0.53) | ARG1ARG2GGT1KDM4EMAPK1 | |
| SCHEMBL202490 | 0.79 | ARG1 (0.47) | ARG1ARG2GGT1TDP1FFAR1 | |
| SCHEMBL161929 | 0.79 | ARG1 (0.47) | ARG1ARG2GGT1TDP1FFAR1 | |
| SCHEMBL6431682 | 0.79 | ARG1 (0.47) | ARG1ARG2GGT1TDP1FFAR1 | |
| SCHEMBL7909629 | 0.79 | ARG1 (0.47) | ARG1ARG2GGT1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534668-B1 | CRYSTALLINE SOLID FORM OF (2S-5Z)-2-AMINO-7-(ETHANIMIDOYLAMINO)-2-METHYLHEPT-5-ENOIC ACID | PHARMACIA CORP (US) | 2012-05-02 | — | — | EP | disclosed |