SCHEMBL202490

SCHEMBL202490

C[C@@](N)(CCCNC(=N)N)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 2/20 0.47
ARG2 P78540 1/20 0.47
GGT1 P19440 1/20 0.43
ALOX15 P16050 1/20 0.38
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KDM4C Q9H3R0 1/20 0.33
NOS2 P35228 4/20 0.32
NOS1 P29475 2/20 0.32
NOS3 P29474 1/20 0.32
BLM P54132 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
EPHX1 P07099 1/20 0.31
ALB P02768 1/20 0.31
FFAR1 O14842 1/20 0.31
CPT2 P23786 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6431682 1.00 ARG1 (0.47) ARG1ARG2GGT1ALOX15MEN1
SCHEMBL161929 1.00 ARG1 (0.47) ARG1ARG2GGT1ALOX15MEN1
Hydrochloric Acid SCHEMBL11674295 0.98 ARG1 (0.46) ARG1ARG2GGT1ALOX15MEN1
Hydrochloric Acid SCHEMBL11674300 0.98 ARG1 (0.46) ARG1ARG2GGT1ALOX15MEN1
SCHEMBL1388309 0.87 ALOX15 (0.39) ARG1ARG2ALOX15MEN1CYP1A2
SCHEMBL1388310 0.87 ALOX15 (0.39) ARG1ARG2ALOX15MEN1CYP1A2
SCHEMBL10078923 0.86 ALOX15 (0.38) ARG1ARG2ALOX15MEN1CYP1A2
SCHEMBL1504428 0.85 ARG1 (0.50) ARG1ARG2GGT1ALOX15MEN1
SCHEMBL20978268 0.85 ARG1 (0.50) ARG1ARG2GGT1ALOX15MEN1
SCHEMBL1455221 0.85 ARG1 (0.50) ARG1ARG2GGT1ALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1804 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090215895-A1 Therapeutic and carrier molecules PEPLIN BIOLIPIDS PTY LTD (AU) 2009-08-27 US claimed
EP-1718602-A4 THERAPEUTIC AND CARRIER MOLECULES PEPLIN BIOLIPIDS PTY LTD (AU) 2007-12-12 EP claimed
US-7256172-B1 Method of treatment and agents useful for same THE UNIVERSITY OF MELBOURNE (AU) 2007-08-14 US claimed
EP-1718602-A1 THERAPEUTIC AND CARRIER MOLECULES Peplin Biolipids Pty Ltd. (AU) 2006-11-08 EP claimed
US-7070969-B1 Plasmin inhibitors from the australian brown snake Pseudonaja textilis textilis THE UNIVERSITY OF QUEENSLAND (AU) 2006-07-04 US claimed
WO-2005073164-A1 THERAPEUTIC AND CARRIER MOLECULES PEPLIN BIOLIPIDS PTY LTD (AU) 2005-08-11 WO claimed
CN-122094704-A Formulations for oral administration of active agents comprising a combination of acid-neutralizing polymer and non-polymeric material 2026-05-26 CN disclosed
WO-2026085582-A1 PROTEIN CAGES THE UNIVERSITY OF SYDNEY (AU) 2026-04-30 WO disclosed
EP-4627079-A2 THERMOSTABLE BINDING SCAFFOLDS Nectagen, Inc. (US) 2025-10-08 EP disclosed
CN-120202191-A Inhibitors of prostate specific membrane antigen and uses thereof 上海先通生物科技有限公司 2025-06-24 CN disclosed
EP-4551563-A2 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2025-05-14 EP disclosed
WO-2025091087-A1 BISPECIFIC PROTEINS MONASH UNIVERSITY (AU) 2025-05-08 WO disclosed
CN-119816487-A FC conjugates comprising CD73 inhibitors and uses thereof 奇达拉治疗公司 2025-04-11 CN disclosed
WO-1997004091-A1 NOVEL RECEPTOR LIGANDS AND GENETIC SEQUENCES ENCODING SAME AMRAD OPERATIONS PTY. LTD. (AU) 1997-02-06 WO disclosed
EP-0745092-A1 PEPTIDE INHIBITORS OF UROKINASE RECEPTOR ACTIVITY CHIRON CORPORATION (US) 1996-12-04 EP disclosed
EP-0672049-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1995-09-20 EP disclosed
WO-1994028014-A2 PEPTIDE INHIBITORS OF UROKINASE RECEPTOR ACTIVITY CHIRON CORPORATION (US) 1994-12-08 WO disclosed
WO-1994011388-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1994-05-26 WO disclosed
WO-1994003483-A1 ENDOTHELIN RECEPTOR-BINDING COMPOUNDS CHIRON CORPORATION (US) 1994-02-17 WO disclosed
US-4061542-A 2-Methyl-L-arginine produced by cultivating streptomyces strain HOFFMANN-LA ROCHE INC. (US) 1977-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215895-A1 Therapeutic and carrier molecules PHKG1, PHKG2, DGKB ARG1 4434/4885ARG2 2829/4885GGT1 1211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.