SCHEMBL27132479

SCHEMBL27132479

Cc1ccc(-c2cnnc(N3CCN(CC(=O)NC4CCCCC4)CC3)n2)cc1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CYP11B2 P19099 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lorundrostat SCHEMBL18489931 0.91 CYP11B2 (1.00) CYP11B2
Lorundrostat SCHEMBL29501060 0.91 CYP11B2 (1.00) CYP11B2
Lorundrostat SCHEMBL25323514 0.91 CYP11B2 (1.00) CYP11B2
Lorundrostat SCHEMBL29536765 0.90 CYP11B2 (0.98) CYP11B2
SCHEMBL18489903 0.90 CYP11B2 (1.00) CYP11B2
Lorundrostat SCHEMBL25323633 0.90 CYP11B2 (0.98) CYP11B2
Lorundrostat SCHEMBL25323630 0.90 CYP11B2 (0.98) CYP11B2
SCHEMBL17207663 0.89 CYP11B2 (0.73) CYP11B2
SCHEMBL18502893 0.86 CYP11B2 (0.76) CYP11B2
SCHEMBL18502894 0.84 CYP11B2 (0.74) CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024044594-A2 METHODS OF TREATING HYPERTENSION WITH A COMBINATION OF AN ALDOSTERONE SYNTHASE INHIBITOR AND A DIURETIC Mineralys Therapeutics, Inc. (US) 2024-02-29 — — WO disclosed
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