Lorundrostat

Lorundrostat

SCHEMBL25323514

CC(=O)NC1CCC(NC(=O)CN2CCN(c3nncc(-c4ccc(C)cc4)n3)CC2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CYP11B2 P19099 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lorundrostat SCHEMBL18489931 1.00 CYP11B2 (1.00) CYP11B2
Lorundrostat SCHEMBL29501060 1.00 CYP11B2 (1.00) CYP11B2
Lorundrostat SCHEMBL29536765 0.99 CYP11B2 (0.98) CYP11B2
Lorundrostat SCHEMBL25323630 0.99 CYP11B2 (0.98) CYP11B2
Lorundrostat SCHEMBL25323633 0.99 CYP11B2 (0.98) CYP11B2
SCHEMBL27132479 0.91 CYP11B2 (0.84) CYP11B2
SCHEMBL18489903 0.90 CYP11B2 (1.00) CYP11B2
SCHEMBL18502893 0.87 CYP11B2 (0.76) CYP11B2
SCHEMBL18489968 0.86 CYP11B2 (0.84) CYP11B2
SCHEMBL28557913 0.86 CYP11B2 (0.84) CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008756-A1 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2026-01-08 — — US claimed
EP-4623917-A2 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-10-01 — — EP claimed
CN-117957213-A Soluble pharmaceutical compositions comprising salts of disubstituted 1,2, 4-triazine compounds 矿物疗法公司 2024-04-30 — — CN claimed
US-20230365513-A1 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2023-11-16 — — US claimed
EP-4215244-A1 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2023-07-26 — — EP claimed
CN-116323569-A Salts of triazine compounds, crystalline forms thereof, and methods of manufacture 田边三菱制药株式会社 2023-06-23 — — CN claimed
CN-106232587-B Disubstituted 1,2, 4-triazine compounds 田边三菱制药株式会社 2021-04-13 — — CN claimed
US-20260008756-A1 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2026-01-08 — — US disclosed
US-20260008756-A1 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2026-01-08 — — US disclosed
EP-4623917-A3 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-12-03 — — EP disclosed
EP-4623917-A2 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-10-01 — — EP disclosed
EP-4623917-A2 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-10-01 — — EP disclosed
CN-117957213-A Soluble pharmaceutical compositions comprising salts of disubstituted 1,2, 4-triazine compounds 矿物疗法公司 2024-04-30 — — CN disclosed
US-20230365513-A1 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2023-11-16 — — US disclosed
US-20230365513-A1 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2023-11-16 — — US disclosed
EP-4215244-A1 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2023-07-26 — — EP disclosed
EP-4215244-A1 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2023-07-26 — — EP disclosed
CN-116323569-A Salts of triazine compounds, crystalline forms thereof, and methods of manufacture 田边三菱制药株式会社 2023-06-23 — — CN disclosed
CN-116323569-A Salts of triazine compounds, crystalline forms thereof, and methods of manufacture 田边三菱制药株式会社 2023-06-23 — — CN disclosed
CN-106232587-B Disubstituted 1,2, 4-triazine compounds 田边三菱制药株式会社 2021-04-13 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365513-A1 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR REN, STS, HSD11B1 CYP11B2 10/4885
US-20260008756-A1 TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR REN, HSD11B2, HSD11B1 CYP11B2 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback