Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | SLC1A5 | Q15758 | 12/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26987838 | 1.00 | LTA4H (0.47) | LTA4HDPP4SLC1A5ALOX5KDM4E | |
| SCHEMBL26987958 | 0.84 | HDAC3 (0.55) | SLC1A5HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27125342 | 0.84 | HDAC3 (0.55) | SLC1A5HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27125658 | 0.83 | CYP2C19 (0.49) | SLC1A5ALDH1A1 | |
| SCHEMBL26987705 | 0.83 | CYP2C19 (0.49) | SLC1A5ALDH1A1 | |
| SCHEMBL27131855 | 0.79 | SLC1A5 (0.74) | SLC1A5 | |
| SCHEMBL26987832 | 0.79 | SLC1A5 (0.74) | SLC1A5 | |
| SCHEMBL26987594 | 0.70 | NNMT (0.54) | SLC1A5 | |
| SCHEMBL27130058 | 0.70 | NNMT (0.54) | SLC1A5 | |
| SCHEMBL9584558 | 0.70 | CYP2C19 (0.56) | ALDH1A1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010732-A1 | SMALL MOLECULE INHIBITORS OF GLUTAMINE TRANSPORTER ASCT2 AND METHODS OF USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-01-11 | — | — | WO | disclosed |