Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 2/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24072414 | 0.85 | CSNK2A2 (0.41) | IKBKETBK1CSNK2A2CSNK2A1KDR | |
| SCHEMBL25063293 | 0.83 | PRSS12 (0.41) | KDM4EMAPTCSNK2A2CSNK2A1ALDH1A1 | |
| SCHEMBL25063129 | 0.82 | CSNK2A2 (0.53) | CSNK2A2CSNK2A1KDRSCDNPC1 | |
| SCHEMBL24074140 | 0.81 | NPC1 (0.56) | KDM4EMAPTKDRALDH1A1NPC1 | |
| SCHEMBL24072749 | 0.80 | STAT3 (0.41) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL29056990 | 0.79 | STAT3 (0.59) | MAPTTHRBRECQLALDH1A1NPC1 | |
| SCHEMBL30339343 | 0.79 | STAT3 (0.59) | MAPTTHRBRECQLALDH1A1NPC1 | |
| SCHEMBL27135218 | 0.77 | CYP1A2 (0.55) | KDM4EMAPTKDRSCDALDH1A1 | |
| SCHEMBL25063447 | 0.77 | RAB9A (0.41) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL24073708 | 0.75 | KDR (0.64) | KDM4ECSNK2A2CSNK2A1KDRSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | IKBKE 1854/4885TBK1 1684/4885KDM4E 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.