SCHEMBL2713635

SCHEMBL2713635

[CH2]CN1C(=O)NC(C)(C)C1=O

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.68
KMT2A Q03164 4/20 0.57
PDE4A P27815 1/20 0.50
PDE4B Q07343 1/20 0.50
PDE4C Q08493 1/20 0.50
PDE4D Q08499 1/20 0.50
MEN1 O00255 3/20 0.47
TSHR P16473 2/20 0.47
LMNA P02545 1/20 0.47
KDM4E B2RXH2 1/20 0.46
PADI4 Q9UM07 1/20 0.45
FPR2 P25090 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALDH1A1 P00352 4/20 0.43
PLA2G7 Q13093 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11677768 0.81 POLB (0.74) POLBKMT2APDE4APDE4BPDE4C
SCHEMBL11378894 0.81 POLB (1.00) POLBKMT2APDE4APDE4BPDE4C
SCHEMBL5584023 0.79 POLB (0.71) POLBKMT2APDE4APDE4BPDE4C
SCHEMBL11847614 0.77 POLB (0.68) POLBKMT2APDE4APDE4BPDE4C
SCHEMBL19404136 0.77 POLB (0.68) POLBKMT2APDE4APDE4BPDE4C
SCHEMBL561241 0.77 POLB (0.68) POLBKMT2APDE4APDE4BPDE4C
SCHEMBL11694927 0.77 POLB (0.68) POLBKMT2APDE4APDE4BPDE4C
SCHEMBL13753309 0.76 POLB (0.65) POLBKMT2APDE4APDE4BPDE4C
SCHEMBL9787811 0.76 POLB (0.65) POLBKMT2APDE4APDE4BPDE4C
SCHEMBL11694716 0.76 POLB (0.65) POLBKMT2APDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9248117-B2 Substituted N,N-dihaloamines as antimicrobials NOVABAY PHARMACEUTICALS, INC. (US) 2016-02-02 US disclosed
EP-2341777-B1 ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS NOVABAY PHARMACEUTICALS INC (US) 2015-01-21 EP disclosed
US-8722715-B2 Antimicrobial oxazolidinone, hydantoin and imidazolidinone compositions NovaBay Pharmaceuticals (US) 2014-05-13 US disclosed
EP-2629607-A2 ANTIMICROBIAL POLYETHER AND POLYOL COMPOUNDS NovaBay Pharmaceuticals, Inc. (US) 2013-08-28 EP disclosed
WO-2012054521-A2 ANTIMICROBIAL POLYETHER AND POLYOL COMPOUNDS NOVABAY PHARMACEUTICLAS, INC. (US) 2012-04-26 WO disclosed
US-20100137349-A1 ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS NOVABAY PHARMACEUTICALS, INC. 2010-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137349-A1 ANTIMICROBIAL OXAZOLIDINONE, HYDANTOIN AND IMIDAZOLIDINONE COMPOSITIONS OXA1L, NISCH, ODC1 POLB 1432/4885KMT2A 2188/4885PDE4A 2601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.