Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378894 | 0.83 | POLB (1.00) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL11677768 | 0.83 | POLB (0.74) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL13753309 | 0.82 | POLB (0.65) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL11541792 | 0.79 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL19423838 | 0.79 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL561241 | 0.79 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL27335612 | 0.79 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL2713635 | 0.79 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL11847614 | 0.79 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL11694927 | 0.79 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394056-B1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC (US) | 2021-04-14 | — | — | EP | disclosed |
| US-10689526-B2 | N-halamines compounds as multifunctional additives | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-06-23 | — | — | US | disclosed |
| US-20190055414-A1 | N-HALAMINES COMPOUNDS AS MULTIFUNCTIONAL ADDITIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2019-02-21 | — | — | US | disclosed |
| US-10138379-B2 | N-halamines compounds as multifunctional additives | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-11-27 | — | — | US | disclosed |
| WO-2017165961-A1 | SILANE-BASED ANTIMICROBIAL COATINGS AND METHODS OF MAKING AND USING THE SAME | TRENT UNIVERSITY (CA) | 2017-10-05 | — | — | WO | disclosed |
| US-20170273307-A1 | SILANE-BASED ANTIMICROBIAL COATINGS AND METHODS OF MAKING AND USING THE SAME | UNIV TRENT (CA) | 2017-09-28 | — | — | US | disclosed |
| WO-2017112777-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC (US) | 2017-06-29 | — | — | WO | disclosed |
| US-20170174869-A1 | COMPOSITION, METHOD OF MANUFACTURING COMPOSITION, CURABLE COMPOSITION, CURED FILM, NEAR-INFRARED CUT FILTER, SOLID-STATE IMAGING DEVICE, INFRARED SENSOR, AND CAMERA MODULE | FUJIFILM CORPORATION (JP) | 2017-06-22 | — | — | US | disclosed |
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC | 2017-06-22 | — | — | US | disclosed |
| US-20150166796-A1 | N-Halamines Compounds as Multifunctional Additives | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2015-06-18 | — | — | US | disclosed |
| US-20120174240-A1 | ROLE OF PROTEOGLYCANS IN DRUG DEPENDENCE | SANNA PIETRO P (US) | 2012-07-05 | — | — | US | disclosed |
| US-8211932-B2 | Organic compounds and their uses | NOVARTIS AG (CH) | 2012-07-03 | — | — | US | disclosed |
| US-8119854-B2 | Role of proteoglycans in drug dependence | Sanna, Pietro P. (US) | 2012-02-21 | — | — | US | disclosed |
| US-8119854-B2 | Role of proteoglycans in drug dependence | Sanna, Pietro P. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100331243-A1 | ORGANIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2010-12-30 | — | — | US | disclosed |
| US-20100204159-A1 | ORGANIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2010-08-12 | — | — | US | disclosed |
| US-20100199361-A1 | Role of Proteoglycans in Drug Dependence | Sanna, Pietro Paolo (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100199361-A1 | Role of Proteoglycans in Drug Dependence | Sanna, Pietro Paolo (US) | 2010-08-05 | — | — | US | disclosed |
| US-7276520-B2 | Bicyclic piperidine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20070062884-A1 | N-halamines compounds as multifunctional additives | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166796-A1 | N-Halamines Compounds as Multifunctional Additives | NIT2, AAAS, NACA | POLB 1145/4885KMT2A 303/4885PDE4A 2812/4885 |
| US-20100331243-A1 | ORGANIC COMPOUNDS AND THEIR USES | OAT, OTC, AOX1 | POLB 419/4885KMT2A 3407/4885PDE4A 3448/4885 |
| US-20120174240-A1 | ROLE OF PROTEOGLYCANS IN DRUG DEPENDENCE | OGFR, CSGALNACT1, OPRL1 | POLB 4760/4885KMT2A 3147/4885PDE4A 1761/4885 |
| US-20170273307-A1 | SILANE-BASED ANTIMICROBIAL COATINGS AND METHODS OF MAKING AND USING THE SAME | CUTA, SMURF1, TET1 | POLB 3134/4885KMT2A 1165/4885PDE4A 4576/4885 |
| US-20100199361-A1 | Role of Proteoglycans in Drug Dependence | OGFR, CSGALNACT1, OPRL1 | POLB 4760/4885KMT2A 3147/4885PDE4A 1761/4885 |
| US-10138379-B2 | N-halamines compounds as multifunctional additives | NIT2, AAAS, NACA | POLB 1145/4885KMT2A 303/4885PDE4A 2812/4885 |
| US-20100204159-A1 | ORGANIC COMPOUNDS AND THEIR USES | OAT, OTC, AOX1 | POLB 419/4885KMT2A 3407/4885PDE4A 3448/4885 |
| US-10689526-B2 | N-halamines compounds as multifunctional additives | NIT2, AAAS, NACA | POLB 1145/4885KMT2A 303/4885PDE4A 2812/4885 |
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | MAPK6, MAP3K6, MAPK4 | POLB 1589/4885KMT2A 3544/4885PDE4A 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.