Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378894 | 0.81 | POLB (1.00) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL11677768 | 0.81 | POLB (0.74) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL21208369 | 0.79 | POLB (0.59) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL5584023 | 0.79 | POLB (0.71) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL561241 | 0.77 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL11541792 | 0.77 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL11694927 | 0.77 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL19423838 | 0.77 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL2713635 | 0.77 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C | |
| SCHEMBL11847614 | 0.77 | POLB (0.68) | POLBKMT2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017165961-A1 | SILANE-BASED ANTIMICROBIAL COATINGS AND METHODS OF MAKING AND USING THE SAME | TRENT UNIVERSITY (CA) | 2017-10-05 | — | — | WO | disclosed |
| US-20170273307-A1 | SILANE-BASED ANTIMICROBIAL COATINGS AND METHODS OF MAKING AND USING THE SAME | UNIV TRENT (CA) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170273307-A1 | SILANE-BASED ANTIMICROBIAL COATINGS AND METHODS OF MAKING AND USING THE SAME | CUTA, SMURF1, TET1 | POLB 3134/4885KMT2A 1165/4885PDE4A 4576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.