⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27147882 | 0.92 | — | — | |
| SCHEMBL30780301 | 0.78 | ABL1 (0.32) | — | |
| SCHEMBL27145381 | 0.78 | S1PR2 (0.30) | — | |
| SCHEMBL30780206 | 0.69 | ABL1 (0.32) | — | |
| SCHEMBL27140441 | 0.66 | CSNK2A1 (0.37) | — | |
| SCHEMBL31613256 | 0.66 | CSNK2A1 (0.37) | — | |
| SCHEMBL27145458 | 0.65 | — | — | |
| SCHEMBL27149479 | 0.63 | S1PR2 (0.32) | — | |
| SCHEMBL24666913 | 0.60 | FGFR1 (0.41) | — | |
| SCHEMBL24665035 | 0.57 | FGFR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577546-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | Enliven Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024044713-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-02-29 | — | — | WO | disclosed |