Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315039 | 0.81 | ALOX15 (0.67) | ALOX15HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9570337 | 0.79 | ALOX15 (0.63) | ALOX15HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23530839 | 0.78 | ALOX15 (0.62) | ALOX15HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11330725 | 0.78 | ALOX15 (0.62) | ALOX15HPGDSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11317872 | 0.77 | ALOX15 (0.60) | ALOX15HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14266744 | 0.77 | ALOX15 (0.69) | ALOX15HPGDSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL31312534 | 0.75 | ALOX15 (0.59) | ALOX15HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1398851 | 0.75 | ALOX15 (0.54) | ALOX15HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14256492 | 0.73 | ALOX15 (0.64) | ALOX15HPGDSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11328269 | 0.72 | ALOX15 (0.54) | ALOX15HPGDSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208998-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | UNIVERSITAT DE BARCELONA (ES) | 2024-06-27 | — | — | US | disclosed |
| EP-4326262-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | Fundació Privada Institut d'Investigació Oncològica de Vall Hebron (ES) | 2024-02-28 | — | — | EP | disclosed |
| CN-117320715-A | Compounds for the treatment of hyperproliferative diseases | 瓦尔希伯伦私人肿瘤研究基金会 | 2023-12-29 | — | — | CN | disclosed |
| WO-2022223704-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ ONCOLÒGICA DE VALL HEBRON (ES) | 2022-10-27 | — | — | WO | disclosed |
| EP-4079304-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron (ES) | 2022-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208998-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | VHL, PCNA, HRAS | ALOX15 749/4885HPGD 142/4885SMN1; SMN2 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.