Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597470 | 0.83 | ALOX15 (0.63) | ALOX15SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL11315039 | 0.79 | ALOX15 (0.67) | ALOX15SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL11330725 | 0.79 | ALOX15 (0.62) | ALOX15SMN1; SMN2NPC1RAB9ATSHR | |
| Hydrochloric Acid SCHEMBL11317872 | 0.78 | ALOX15 (0.60) | ALOX15SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL14266744 | 0.78 | ALOX15 (0.69) | ALOX15SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL14256492 | 0.74 | ALOX15 (0.64) | ALOX15SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL9570104 | 0.74 | ALDH1A1 (0.47) | SMN1; SMN2NPC1RAB9ATSHRLMNA | |
| SCHEMBL9597537 | 0.73 | ALOX15 (0.35) | ALOX15SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL3460400 | 0.72 | ALOX15 (0.53) | ALOX15SMN1; SMN2NPC1RAB9ATSHR | |
| Hydrochloric Acid SCHEMBL11328269 | 0.70 | ALOX15 (0.54) | ALOX15SMN1; SMN2NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |