Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 5/20 | 0.54 |
| ▸ | WNT3A | P56704 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32680615 | 1.00 | CTNNB1 (0.54) | CTNNB1WNT3AALDH1A1MAPK1HTT | |
| SCHEMBL31396077 | 0.88 | CTNNB1 (0.68) | CTNNB1WNT3AALDH1A1MAPK1HTT | |
| SCHEMBL23024775 | 0.88 | CTNNB1 (0.68) | CTNNB1WNT3AALDH1A1MAPK1HTT | |
| SCHEMBL21385292 | 0.81 | ALDH1A1 (0.55) | CTNNB1WNT3AALDH1A1MAPK1TSHR | |
| SCHEMBL997623 | 0.81 | CTNNB1 (0.46) | CTNNB1WNT3AALDH1A1MAPK1STAT3 | |
| SCHEMBL15979768 | 0.81 | CTNNB1 (0.82) | CTNNB1WNT3AALDH1A1TSHRLMNA | |
| SCHEMBL27139384 | 0.79 | KDM4E (0.68) | CTNNB1WNT3AALDH1A1MAPK1NPC1 | |
| SCHEMBL26654163 | 0.79 | CTNNB1 (0.57) | CTNNB1WNT3AALDH1A1MAPK1SRD5A2 | |
| SCHEMBL17929673 | 0.76 | CTNNB1 (0.68) | CTNNB1WNT3AALDH1A1TSHRNPC1 | |
| SCHEMBL619634 | 0.76 | MAPK1 (0.78) | CTNNB1ALDH1A1MAPK1SRD5A2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMA INC (US) | 2026-03-05 | — | — | US | disclosed |
| WO-2024044098-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062443-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | C9, SSB, C1S | CTNNB1 3920/4885WNT3A 3812/4885ALDH1A1 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.