Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | STAT3 | P40763 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL27289523 | 0.96 | MAPK1 (0.72) | MAPK1ALDH1A1TSHRSTAT3PKM | |
| SCHEMBL29363947 | 0.94 | KDM4E (0.72) | MAPK1ALDH1A1TSHRSTAT3PKM | |
| SCHEMBL22292225 | 0.94 | KDM4E (0.72) | MAPK1ALDH1A1TSHRSTAT3PKM | |
| SCHEMBL16784086 | 0.94 | KDM4E (0.72) | MAPK1ALDH1A1TSHRSTAT3PKM | |
| SCHEMBL16784085 | 0.94 | KDM4E (0.72) | MAPK1ALDH1A1TSHRSTAT3PKM | |
| SCHEMBL2807412 | 0.94 | KDM4E (0.72) | MAPK1ALDH1A1TSHRSTAT3PKM | |
| SCHEMBL12445338 | 0.94 | KDM4E (0.72) | MAPK1ALDH1A1TSHRSTAT3PKM | |
| SCHEMBL2806009 | 0.94 | KDM4E (0.72) | MAPK1ALDH1A1TSHRSTAT3PKM | |
| SCHEMBL10031399 | 0.94 | KDM4E (0.72) | MAPK1ALDH1A1TSHRSTAT3PKM | |
| SCHEMBL3064183 | 0.92 | ALDH1A1 (0.72) | MAPK1ALDH1A1TSHRSTAT3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 832 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431432-A | Andrographolide diester derivative, preparation method and application | 西北农林科技大学 | 2025-02-14 | — | — | CN | claimed |
| CN-118340765-A | Application of benzamide compound in preparation of wound healing promoting medicine | 广州市朝利良生物科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118271276-A | Naphthalenone derivative for promoting wound healing as well as preparation method and application thereof | 广州市朝利良生物科技有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-115368346-B | 1, 4-benzodioxane-benzimidazole salt compound and synthesis method and application thereof | 曲靖师范学院 | 2024-04-09 | — | — | CN | claimed |
| CN-114057625-B | C2-acyloxy-3-indolinone derivative and preparation method and application thereof | 五邑大学 | 2023-11-24 | — | — | CN | claimed |
| US-20220388975-A1 | SULFONAMIDE BENZAMIDE DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | WEIFANG MEDICAL UNIVERSITY (CN) | 2022-12-08 | — | — | US | claimed |
| CN-115368346-A | 1, 4-benzodioxan-benzimidazole salt compound and synthesis method and application thereof | 曲靖师范学院 | 2022-11-22 | — | — | CN | claimed |
| CN-112939778-B | Coumarin compound ester derivatives, preparation method and application thereof | 西北农林科技大学 | 2022-08-02 | — | — | CN | claimed |
| US-20210395238-A1 | NADPH OXIDASE 4 INHIBITORS | ACTELTION PHARMACEUTICALS LTD (CH) | 2021-12-23 | — | — | US | claimed |
| CN-112939778-A | Coumarin compound ester derivatives, preparation method and application thereof | 西北农林科技大学 | 2021-06-11 | — | — | CN | claimed |
| WO-2004089416-A2 | COMBINATION OF AN 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND AN ANTIHYPERTENSIVE AGENT | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089470-A2 | NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | claimed |
| US-20040138219-A1 | Quinolines and nitrogenated derivative therof substituted in 4-position by a piperidine-containing moiety and their use as antibacterial agents | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-07-15 | — | — | US | claimed |
| WO-2004052919-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | claimed |
| EP-1359908-A1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF SUBSTITUTED IN 4-POSITION BY A PIPERIDINE-CONTAINING MOIETY AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2003-11-12 | — | — | EP | claimed |
| CN-1116271-C | Method of producing 2 -substituted -3, 4 -fused heterocycle benzoic acid | DOW AGROSCIENCES CORP (US) | 2003-07-30 | — | — | CN | claimed |
| WO-2002056882-A1 | QUINOLINES AND NITROGENATED DERIVAIVE THEREOF SUBSTITUTED IN 4-POSITION BY A PIPERIDINE-CONTAINING MOIETY AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-07-25 | — | — | WO | claimed |
| CN-1182075-A | Method of producing 2 -substituted -3, 4 -fused heterocycle benzoic acid | ROHM & HAAS (US) | 1998-05-20 | — | — | CN | claimed |
| EP-0729953-A2 | A process for producing a 2-substituted-3,4-fused heterocyclic benzoic acid | ROHM AND HAAS COMPANY (US) | 1996-09-04 | — | — | EP | claimed |
| EP-0602794-A2 | Insecticidal N'-substituted-N, N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1994-06-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220388975-A1 | SULFONAMIDE BENZAMIDE DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | PCNA, DNA2, HBS1L | MAPK1 3019/4885ALDH1A1 3483/4885TSHR 2578/4885 |
| US-20040138219-A1 | Quinolines and nitrogenated derivative therof substituted in 4-position by a piperidine-containing moiety and their use as antibacterial agents | NCF1, TEAD1, TYMS | MAPK1 3767/4885ALDH1A1 1742/4885TSHR 3653/4885 |
| US-20210395238-A1 | NADPH OXIDASE 4 INHIBITORS | NOX4, NOX1, CYBB | MAPK1 373/4885ALDH1A1 176/4885TSHR 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.