SCHEMBL27140354

SCHEMBL27140354

NC(=S)NNCCNC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 1/20 0.32
TAS2R38 P59533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27596164 0.81 ALDH1A1 (0.37) ALDH1A1HPGDHSD17B10TAS2R38
SCHEMBL15328337 0.73 MEN1 (0.36) ALDH1A1TAS2R38
SCHEMBL5120839 0.73 MEN1 (0.41) ALDH1A1HPGDLMNA
SCHEMBL4047411 0.72 CYP2D6 (0.45) ALDH1A1LMNA
SCHEMBL5128168 0.71 KDM4E (0.41) ALDH1A1HPGDLMNA
SCHEMBL38656309 0.70
SCHEMBL1493634 0.70
SCHEMBL28883694 0.70 PRMT1 (0.30)
SCHEMBL31613206 0.69 CYP2D6 (0.43) ALDH1A1LMNA
SCHEMBL28186081 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024044271-A2 METAL CHELATOR COMPOUNDS, COORDINATION COMPLEXES, AND METHODS OF PREPARATION AND USE THEREOF UNIVERSITY OF PUERTO RICO (US) 2024-02-29 WO disclosed