Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27140995 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1NPSR1NOD2HIF1A | |
| SCHEMBL31709129 | 0.88 | ALDH1A1 (0.39) | KDM4EALDH1A1HIF1AALOX15TDP1 | |
| SCHEMBL31709359 | 0.81 | CHRM3 (0.38) | KDM4EALDH1A1TDP1GAACHRM3 | |
| SCHEMBL27140591 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1ALOX15HTTLMNA | |
| SCHEMBL27140586 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1ALOX15HTTLMNA | |
| SCHEMBL31708812 | 0.77 | CHRM3 (0.35) | ALDH1A1CHRM3 | |
| SCHEMBL31709149 | 0.69 | CHRM2 (0.42) | KDM4EALDH1A1MAPK1GAACHRM2 | |
| SCHEMBL31708790 | 0.68 | ALDH1A1 (0.42) | KDM4EALDH1A1HIF1AALOX15TDP1 | |
| SCHEMBL31464069 | 0.65 | KDM4E (0.63) | KDM4EALDH1A1HIF1AALOX15HTT | |
| Hydrochloric Acid SCHEMBL31464105 | 0.64 | KDM4E (0.62) | KDM4EALDH1A1HIF1AALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043334-A1 | NOVEL PIPERAZINE DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION | 富士フイルム株式会社 | 2024-02-29 | — | — | WO | disclosed |