Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31709129 | 0.83 | ALDH1A1 (0.39) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL11900867 | 0.74 | MPO (0.59) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL9933964 | 0.74 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL659637 | 0.73 | PARP1 (0.46) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL376336 | 0.73 | ALDH1A1 (0.60) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL9933216 | 0.73 | ALDH1A1 (0.72) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL17276773 | 0.73 | ALDH1A1 (0.72) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL30576825 | 0.72 | CHRM2 (0.52) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL8560982 | 0.71 | SMARCA2 (0.45) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL25487194 | 0.71 | MGLL (0.44) | CHRM2CHRM4CHRM1CHRM3VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | CHRM2 4766/4885CHRM4 4852/4885CHRM1 4715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.